Mexican police say they have captured the country's most wanted drug lord, Servando "La Tuta" Gomez.
Mr Gomez, leader of the Knights Templar drug cartel, was arrested in Morelia in Michoacan state without a shot fired, police officials said.
Previously a school teacher, he became one of Mexico's most powerful drug lords and took control of Michoacan.
His capture is a coup for the government of Enrique Pena Nieto in its fight against the drug cartels.
A police spokesman told local media the arrest followed months of intelligence work in the region.
Police reportedly seized nearby properties in the weeks leading up Mr Gomez's capture and arrested several of his associates.
Analysis: Katy Watson, BBC News, Mexico City
There are lots of theories as to the origin of the nickname La Tuta, but it seems that for most it's just another mystery.
While La Tuta's capture may be a coup for the administration of Enrique Pena Nieto, the fallout in the state of Michoacan is not clear. It is a poor and violent part of the country, the battleground between drugs cartels and vigilantes trying to oust them.
As one security expert told me, this was a man who was not just in charge of a drugs empire, he wanted political power too - and in politics you gain as many enemies as you do friends.
Perhaps that is what led to the net closing in in the end?
Meth trade
Known by his nicknames "La Tuta" and "El Profe", Mr Gomez ruled over much of Michoacan state as head of the Knights Templar cartel.
"El Profe" refers to his career as a teacher, while theories abound about the origins of "La Tuta".
Mr Gomez evaded capture for years while other senior members of the gang and rival drug lords were captured or killed.
By the time of his arrest, he had a $2 million (£1.3 million) bounty on his head.
Knights Templar was primarily a drug cartel and it controlled a large part of the lucrative methamphetamine trade in western Mexico.
But it was also known for mixing in business and politics in the region and even took effective control over the state's international port, Lazaro Cardenas, making millions of dollars from illegal mining of iron ore.
A federal government offensive in 2013 saw the Pena Nieto administration wrest back control of Michoacan state from the Knights Templar and rival gangs.
As leader of the biggest cartel in the region, Mr Gomez became the prime target of Mr Pena Nieto's crackdown.
The administration has been criticised for failing to tackle the drug gangs, with vigilante groups forming to take on the dealers illegally.
Unlike many rival gang leaders who carefully avoided the limelight, Mr Gomez regularly gave media interviews and railed against the government in Youtube videos.
Mr Gomez began life in the drug trade as an small-time marijuana dealer, before joining a Michoacan gang called La Familia and rising to a senior level. A split in La Familia led him to form Knights Templar.
A father of at least seven, Mr Gomez was also wanted by US authorities in connection with the 2009 murder of 12 Mexican federal police officers.